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Diena Research Center was established in a Southeast city in France Lyons in 1999, nearby the biggest biologicals research center in the world - Merrill Institute of Biological Products, with more than 20 universities and collagens around.

Diena Posts Research Center has been devoted to research the medical application of hyaluronic acid and found a kind of fill type hyaluronic acid with more than 2.5 million units in the same year.

In 2001, developed a macromolecular hyaluronic acid solution used for ophthalmic surgery.

In 2003, successfully developed a kind of hyaluronic acid solution for stick defying solution after surgery and medicine releasing application.

In 2005, the company began the research in medical beauty care and cosmetic additive, focusing on research of function of micro-molecular hyaluronic acid in intercellular substance and moved the research center to the capital Paris.

In 2007, developed a micro-molecular hyaluronic acid under 0.15 million units and became the second research center who can produce the hyaluronic acid under 0.2 million units.

In 2008, devoted to research of compounds of hyaluronic acids of high and low molecule and successfully obtained a technical breakthrough of functions of hyaluronic acid in intercellular substance.

In March 2009, successfully developed a compound of macromolecular hyaluronic acid above 2.5 million unit and micro-molecular hyaluronic acid under 0.1 million unit, which can make treatment and repair of the cells and intercellular substance.